Solid phase chemical ligation employing a rink amide linker for the synthesis of histone H2B protein.
نویسندگان
چکیده
Presented here is a solid phase chemical ligation strategy employing native chemical ligation and the commercially available Rink-amide linker as a key element in our approach. The method was applied for the synthesis of histone H2B, which sets the ground for the rapid preparation of posttranslationally modified analogues of this protein.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 83 شماره
صفحات -
تاریخ انتشار 2014